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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Lou Rosário | 122 | 1996-2004 | |
| 2 | Lee McClendon | 98 | 1988-1994 | |
| 3 | Jorge Medrano | 97 | 1984-1997 | |
| 4 | George MacQuey | 96 | 1997-2007 | |
| 5 | Tim Lucas# | 90 | 2013-2014 | |
| 6 | Raúl Otero | 88 | 1960-1974 | |
| 7 | Andrew Hardy | 78 | 1959-1973 | |
| 8 | Oliver Frazier | 76 | 1981-1984 | |
| 8 | Fred Thompson | 76 | 1970-1976 | |
| 10 | J.R. Hale# | 75 | 2006-2014 | |
| 11 | Gary Burris | 72 | 1972-1981 | |
| 12 | Peter Watson# | 68 | 2005-2014 | |
| 13 | Ray Hebert | 67 | 1982-1992 | |
| 14 | Hiang-ta Jung | 66 | 1992-2002 | |
| 14 | Josh Miller | 66 | 1974-1990 | |
| 16 | Ethan Widener | 65 | 2005-2010 | |
| 16 | Hak-su Yi | 65 | 2003-2008 | |
| 18 | Héctor Alvarado | 62 | 1974-1976 | |
| 18 | Manuel Valadez# | 62 | 2007-2014 | |
| 20 | Ángel Barrón# | 61 | 2008-2010 | |
| 21 | Joel Hall# | 60 | 2012-2014 | |
| 22 | Arnold Ayala# | 59 | 2008-2012 | |
| 22 | Jason Clay# | 59 | 2003-2011 | |
| 22 | Jake Kendall# | 59 | 2007-2010 | |
| 22 | Marcos Robles# | 59 | 2009-2014 | |
| 26 | Damián Castellanos# | 58 | 2003-2013 | |
| 26 | José Padilla# | 58 | 2005-2013 | |
| 28 | Luis Cuellar# | 57 | 2013-2014 | |
| 28 | José Montaño | 57 | 1982-1986 | |
| 30 | Xavier Bartlett | 56 | 1997-2004 | |
| 30 | Nelson Hernández# | 56 | 2007-2013 | |
| 30 | Carlos Rivas | 56 | 1980-1986 | |
| 33 | Pat Bryan# | 55 | 2008-2014 | |
| 33 | Larry Duder# | 55 | 2007-2014 | |
| 33 | Andrés López# | 55 | 2005-2008 | |
| 33 | Gordon Tapia | 55 | 1998-2008 | |
| 37 | Joselito Cota | 54 | 1972-1983 | |
| 37 | Jason Dodson | 54 | 1989-1992 | |
| 37 | Willard Hart | 54 | 1998-2003 | |
| 37 | Clint Lake | 54 | 1971-1975 | |
| 37 | Kenny Viccars# | 54 | 2000-2004 | |
| 37 | Rickey Wade | 54 | 1979-1990 | |
| 37 | Guy White# | 54 | 2008-2014 | |
| 44 | Pedro Castillo | 53 | 1988-1993 | |
| 44 | Bartolo Guerra# | 53 | 2009-2014 | |
| 46 | Roosevelt Jensen# | 52 | 2009-2011 | |
| 47 | Cole Ritchie# | 51 | 2003-2007 | |
| 47 | Ramón Ruíz | 51 | 2002-2007 | |
| 49 | Robby Bradford# | 50 | 2006-2010 | |
| 49 | Gabriel Jaramillo# | 50 | 2002-2005 | |
| 49 | Ryan Schneider | 50 | 1968-1973 | |
| 52 | Jorge Castro# | 49 | 2009-2011 | |
| 53 | Stewart King | 48 | 1984-2000 | |
| 53 | Ramón Pasquetto# | 48 | 2009-2011 | |
| 53 | Bob Rogers | 48 | 1985-1993 | |
| 56 | Daniel Arreola# | 47 | 2007-2014 | |
| 56 | José Martínez# | 47 | 2001-2006 | |
| 56 | Esteban Pérez# | 47 | 2006-2009 | |
| 59 | Don Brown# | 46 | 1999-2014 | |
| 59 | Alejandro Pérez# | 46 | 2012-2014 | |
| 59 | Tom Smith | 46 | 1974-1984 | |
| 62 | Chris Boswell | 45 | 1975-1978 | |
| 62 | Tommy Owens | 45 | 1987-1994 | |
| 64 | Steve Bass | 44 | 1973-1976 | |
| 64 | Sebastiano Elías# | 44 | 2007-2009 | |
| 64 | Gary Gilbert | 44 | 1988-1991 | |
| 64 | Patrick Hensley# | 44 | 2008-2013 | |
| 64 | James Jacobs | 44 | 1975-1977 | |
| 64 | Brian Jenkins# | 44 | 2012-2014 | |
| 64 | Aurelio Martínez# | 44 | 2011-2014 | |
| 64 | Miguel Mata# | 44 | 2003-2013 | |
| 64 | Ernesto Rodríguez | 44 | 1971-1973 | |
| 64 | Jeffery Taylor | 44 | 1999-2004 | |
| 74 | Tom Hansen# | 43 | 2010-2014 | |
| 74 | António Javier# | 43 | 2009-2014 | |
| 74 | Morgan MacKinney | 43 | 1970-1987 | |
| 74 | Ray Martin | 43 | 2004-2013 | |
| 74 | Matt Miller | 43 | 1971-1981 | |
| 74 | Roberto Rosales# | 43 | 2008-2013 | |
| 74 | Francisco Solís | 43 | 2001-2005 | |
| 81 | Travis Bennett | 42 | 1992-1994 | |
| 81 | Scotty Carey | 42 | 1971-1974 | |
| 81 | Juan Castillo | 42 | 1962-1976 | |
| 81 | António González# | 42 | 2002-2014 | |
| 81 | John Horton | 42 | 1997-2001 | |
| 81 | Jorge Lerma# | 42 | 2006-2009 | |
| 81 | Allan Murphy | 42 | 1996-2005 | |
| 81 | Otis Roberts# | 42 | 2006-2012 | |
| 81 | Sam Samways | 42 | 1979-1983 | |
| 81 | Mauro Torres | 42 | 1997-2000 | |
| 91 | Leonardo Andujar# | 41 | 2007-2014 | |
| 91 | Andrés Arroyo | 41 | 1989-2002 | |
| 91 | Shigemori Hirano | 41 | 1976-1980 | |
| 91 | Ken Jackson# | 41 | 2008-2014 | |
| 91 | Ernesto Luna# | 41 | 2009-2012 | |
| 91 | Pedro Maes# | 41 | 2005-2009 | |
| 91 | Pedro Manuel | 41 | 1996-2010 | |
| 91 | Miguel Martínez# | 41 | 2008-2014 | |
| 91 | Tom McCabe# | 41 | 2009-2014 | |
| 91 | Glenn Moore | 41 | 1972-1976 |
