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| Second Basemen Career RBIs Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | RBIs | PA | Years | Single Season Leaderboard |
| 1. | Sergio Rondon | 390 | 2341 | 1952-1955 | |
| 2. | Joe Whelan | 382 | 2407 | 1952-1955 | |
| 3. | Brian Underwood | 361 | 2216 | 1952-1955 | |
| 4. | Dudley Langworthy | 338 | 2247 | 1952-1955 | |
| 5. | Walter Salgado | 318 | 2260 | 1952-1955 | |
| 6. | Ryan Good | 295 | 2231 | 1952-1955 | |
| 7. | Russ Witham | 258 | 1869 | 1952-1955 | |
| 8. | Toby Paschke | 256 | 2201 | 1952-1955 | |
| 9. | James Carrillo | 227 | 2102 | 1952-1955 | |
| 10. | Gregory Kuhn | 225 | 1775 | 1952-1955 | |
| 11. | Claude Ring | 220 | 1843 | 1952-1955 | |
| 12. | Craig Wright | 206 | 1307 | 1952-1955 | |
| 13. | Joseph Stovall | 204 | 1551 | 1952-1954 | |
| 14. | Francis Gaston | 202 | 2102 | 1952-1955 | |
| 15. | Felix Bronner | 198 | 2067 | 1952-1955 | |
| 16. | Michael Mitchell | 190 | 1229 | 1952-1955 | |
| 17. | Andrea Bader | 175 | 1617 | 1952-1955 | |
| 18. | Jason Seger | 169 | 1268 | 1953-1955 | |
| 19. | Rupert Witty | 162 | 1262 | 1952-1955 | |
| 20. | Edward Shiflett | 161 | 1938 | 1952-1955 | |
| 21. | Kenneth Curry | 141 | 1026 | 1952-1955 | |
| 22. | David Burner | 139 | 1288 | 1953-1955 | |
| 23. | Michael Nagy | 122 | 1133 | 1952-1955 | |
| 24. | John Rooks | 108 | 971 | 1952-1955 | |
| 25. | David Mefford | 92 | 718 | 1952-1955 | |
| 26. | Casimiro Dominguez | 86 | 619 | 1953-1955 | |
| 27. | Ramon Dearmas | 74 | 763 | 1953-1955 | |
| Robert George | 74 | 571 | 1952-1955 | ||
| 29. | William Pettitt | 67 | 858 | 1952-1955 | |
| Frank Hardin | 67 | 732 | 1952-1953 | ||
| 31. | Eric Peck | 60 | 414 | 1952-1955 | |
| 32. | Jarod Reed | 59 | 530 | 1952-1955 | |
| 33. | Rickey Hunziker | 57 | 400 | 1952-1953 | |
| 34. | Joseph Smith | 56 | 697 | 1952-1955 | |
| 35. | Jonathan Irick | 36 | 464 | 1955-1955 | |
| Scott Ewing | 36 | 301 | 1952-1955 | ||
| 37. | Adam Washington | 27 | 288 | 1952-1955 | |
| Antonio Zubiri | 27 | 189 | 1953-1954 | ||
| 39. | Brian Scudder | 24 | 153 | 1953-1953 | |
| 40. | Bill Hollins | 22 | 341 | 1955-1955 | |
| John Reyes | 22 | 247 | 1955-1955 | ||
| 42. | Jaime Gall | 20 | 163 | 1952-1955 | |
| 43. | William Waguespack | 19 | 149 | 1952-1955 | |
| 44. | William Park | 14 | 180 | 1952-1953 | |
| 45. | Edwin Carter | 11 | 130 | 1953-1954 | |
| 46. | Bernal Morales | 9 | 51 | 1953-1955 | |
| 47. | Harry Jones | 6 | 36 | 1953-1955 | |
| 48. | Odis Marcial | 5 | 106 | 1954-1954 | |
| Timothy Harrison | 5 | 21 | 1953-1954 | ||
| 50. | Donald Steve | 3 | 15 | 1955-1955 | |
| 51. | Kristofer Hallam | 2 | 10 | 1955-1955 | |
| 52. | Bruce Pounders | 1 | 14 | 1954-1954 | |
| John Morvant | 1 | 43 | 1952-1952 | ||
| Vincent Chapel | 1 | 12 | 1952-1952 |
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