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| Second Basemen Career Innings Played Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Innings Played | IP | Years | Single Season Leaderboard |
| 1. | Brian Underwood | 4360.7 | 4360.7 | 1952-1955 | |
| 2. | Toby Paschke | 4329.0 | 4329.0 | 1952-1955 | |
| 3. | Walter Salgado | 4055.9 | 4055.9 | 1952-1955 | |
| 4. | James Carrillo | 3990.3 | 3990.3 | 1952-1955 | |
| 5. | Francis Gaston | 3914.3 | 3914.3 | 1952-1955 | |
| 6. | Felix Bronner | 3522.3 | 3522.3 | 1952-1955 | |
| 7. | Andrea Bader | 3492.7 | 3492.7 | 1952-1955 | |
| 8. | Claude Ring | 3449.0 | 3449.0 | 1952-1955 | |
| 9. | Ryan Good | 3243.3 | 3243.3 | 1952-1955 | |
| 10. | Dudley Langworthy | 3238.3 | 3238.3 | 1952-1955 | |
| 11. | Edward Shiflett | 3217.0 | 3217.0 | 1952-1955 | |
| 12. | Gregory Kuhn | 3215.7 | 3215.7 | 1952-1955 | |
| 13. | Joseph Stovall | 3191.7 | 3191.7 | 1952-1954 | |
| 14. | Joe Whelan | 2937.8 | 2937.8 | 1952-1955 | |
| 15. | Craig Wright | 2534.7 | 2534.7 | 1952-1955 | |
| 16. | David Burner | 2455.3 | 2455.3 | 1953-1955 | |
| 17. | Sabino Martinez | 2300.3 | 2300.3 | 1952-1955 | |
| 18. | Michael Nagy | 2282.0 | 2282.0 | 1952-1955 | |
| 19. | Jason Seger | 2224.0 | 2224.0 | 1953-1955 | |
| 20. | John Rooks | 2055.0 | 2055.0 | 1952-1955 | |
| 21. | Sergio Rondon | 1882.7 | 1882.7 | 1953-1955 | |
| 22. | Kenneth Curry | 1835.7 | 1835.7 | 1952-1955 | |
| 23. | Stanton Jakubowski | 1759.0 | 1759.0 | 1952-1954 | |
| 24. | Michael Mitchell | 1686.3 | 1686.3 | 1952-1955 | |
| 25. | Ramon Dearmas | 1671.0 | 1671.0 | 1953-1955 | |
| 26. | John Bouffard | 1641.9 | 1641.9 | 1952-1955 | |
| 27. | William Pettitt | 1503.0 | 1503.0 | 1952-1955 | |
| 28. | Rupert Witty | 1318.7 | 1318.7 | 1952-1955 | |
| 29. | Casimiro Dominguez | 1179.0 | 1179.0 | 1953-1955 | |
| 30. | Frank Hardin | 1131.7 | 1131.7 | 1952-1953 | |
| 31. | Russ Witham | 1082.3 | 1082.3 | 1954-1955 | |
| 32. | David Mefford | 1075.0 | 1075.0 | 1952-1955 | |
| 33. | Daniel Staudt | 1016.7 | 1016.7 | 1953-1955 | |
| 34. | Bill Mangels | 891.3 | 891.3 | 1952-1955 | |
| 35. | Joseph Smith | 847.1 | 847.1 | 1952-1955 | |
| 36. | Douglas Thornton | 841.7 | 841.7 | 1952-1955 | |
| 37. | Eric Peck | 831.0 | 831.0 | 1952-1955 | |
| 38. | Rickey Hunziker | 807.3 | 807.3 | 1952-1953 | |
| 39. | Bill Hollins | 791.7 | 791.7 | 1955-1955 | |
| 40. | James Mickel | 771.7 | 771.7 | 1952-1955 | |
| 41. | Emerson Freer | 700.0 | 700.0 | 1952-1955 | |
| 42. | Tuan Kluge | 699.0 | 699.0 | 1952-1955 | |
| 43. | Robert George | 668.3 | 668.3 | 1952-1955 | |
| 44. | Bradley Nelson | 665.7 | 665.7 | 1952-1955 | |
| 45. | Renato Diaz | 600.3 | 600.3 | 1952-1955 | |
| 46. | John Reyes | 573.3 | 573.3 | 1955-1955 | |
| 47. | Anthony Ojeda | 552.7 | 552.7 | 1952-1955 | |
| 48. | Richard Davis | 530.7 | 530.7 | 1952-1955 | |
| 49. | Pete Rustin | 503.4 | 503.4 | 1952-1955 | |
| 50. | Adam Washington | 488.0 | 488.0 | 1952-1953 | |
| 51. | David Hindman | 462.3 | 462.3 | 1955-1955 | |
| 52. | Michael Dukes | 427.3 | 427.3 | 1952-1955 | |
| 53. | Jarod Reed | 423.3 | 423.3 | 1952-1955 | |
| 54. | Tim Wilkens | 418.7 | 418.7 | 1952-1955 | |
| 55. | Vicente Loehr | 398.7 | 398.7 | 1952-1955 | |
| 56. | Raymond Stephens | 392.0 | 392.0 | 1955-1955 | |
| 57. | Antonio Zubiri | 383.0 | 383.0 | 1953-1954 | |
| 58. | William Park | 378.6 | 378.6 | 1952-1953 | |
| 59. | Bill Brier | 361.0 | 361.0 | 1952-1955 | |
| 60. | Brian Scudder | 324.0 | 324.0 | 1953-1953 | |
| 61. | Robert Raines | 299.0 | 299.0 | 1952-1955 | |
| 62. | Bernie Opitz | 280.7 | 280.7 | 1955-1955 | |
| 63. | Amando Llorent | 251.0 | 251.0 | 1953-1953 | |
| 64. | Jaime Gall | 204.0 | 204.0 | 1952-1955 | |
| 65. | William Waguespack | 198.0 | 198.0 | 1952-1955 | |
| Wilfredo Santamaria | 198.0 | 198.0 | 1952-1954 | ||
| 67. | Andrew Ostrander | 195.7 | 195.7 | 1954-1955 | |
| 68. | Wallace Longley | 191.0 | 191.0 | 1952-1955 | |
| 69. | Jason Herrera | 176.3 | 176.3 | 1954-1955 | |
| 70. | John Mota | 149.7 | 149.7 | 1953-1955 | |
| 71. | Pedro Rico | 142.3 | 142.3 | 1953-1955 | |
| 72. | Edwin Carter | 132.3 | 132.3 | 1953-1954 | |
| 73. | Alvin Carlucci | 129.7 | 129.7 | 1954-1955 | |
| 74. | Mark Yokley | 106.3 | 106.3 | 1952-1955 | |
| 75. | John Thomas | 98.7 | 98.7 | 1952-1953 | |
| 76. | Shawn Cosentino | 92.0 | 92.0 | 1955-1955 | |
| 77. | John Morvant | 90.0 | 90.0 | 1952-1952 | |
| 78. | Abraham Mendoza | 72.0 | 72.0 | 1954-1954 | |
| 79. | Odis Marcial | 67.0 | 67.0 | 1954-1954 | |
| 80. | Alonzo Parisi | 63.0 | 63.0 | 1952-1954 | |
| 81. | Luis Villalba | 62.0 | 62.0 | 1953-1953 | |
| Robert Todd | 62.0 | 62.0 | 1952-1952 | ||
| 83. | John Kohut | 61.0 | 61.0 | 1954-1954 | |
| 84. | Chet Burton | 61.0 | 61.0 | 1952-1955 | |
| 85. | Bernal Morales | 59.7 | 59.7 | 1953-1955 | |
| 86. | Howard Stull | 57.0 | 57.0 | 1952-1953 | |
| 87. | Cody Morris | 56.3 | 56.3 | 1955-1955 | |
| 88. | Franklin Grimshaw | 54.0 | 54.0 | 1953-1954 | |
| 89. | Timothy Harrison | 50.7 | 50.7 | 1953-1954 | |
| 90. | Tommy Dupras | 50.0 | 50.0 | 1955-1955 | |
| 91. | Daniel St. George | 49.3 | 49.3 | 1953-1953 | |
| 92. | Mark Millican | 49.0 | 49.0 | 1953-1955 | |
| 93. | Victor Espinoza | 48.0 | 48.0 | 1954-1955 | |
| Patrick Nehring | 48.0 | 48.0 | 1954-1955 | ||
| George Sanchez | 48.0 | 48.0 | 1952-1952 | ||
| 96. | Harry Jones | 42.0 | 42.0 | 1953-1955 | |
| 97. | Donald Steve | 31.0 | 31.0 | 1955-1955 | |
| 98. | Donald Pan | 28.0 | 28.0 | 1955-1955 | |
| Robert Lococo | 28.0 | 28.0 | 1955-1955 | ||
| Eldridge Lane | 28.0 | 28.0 | 1953-1953 |
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