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| Third Basemen Career Strikeouts Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Strikeouts | PA | Years | Single Season Leaderboard |
| 1. | Christopher Sykes | 371 | 2368 | 1952-1955 | |
| 2. | Michael Sanroman | 361 | 1687 | 1952-1955 | |
| 3. | George Hoyle | 360 | 2319 | 1952-1955 | |
| 4. | Stanton Jakubowski | 295 | 2068 | 1952-1955 | |
| 5. | Juan Soderberg | 276 | 1972 | 1952-1955 | |
| 6. | Vinny Velazquez | 272 | 2412 | 1952-1955 | |
| Wallace Longley | 272 | 1451 | 1952-1955 | ||
| 8. | Brian Westberry | 270 | 2214 | 1952-1955 | |
| 9. | Bobby Miles | 258 | 1439 | 1952-1955 | |
| 10. | Timothy Barcia | 249 | 1478 | 1952-1955 | |
| 11. | Jason Fowler | 244 | 1683 | 1952-1955 | |
| 12. | Daniel Staudt | 240 | 1766 | 1952-1955 | |
| 13. | Stephen Wakeman | 236 | 2221 | 1952-1955 | |
| 14. | Keith Vera | 235 | 1364 | 1952-1955 | |
| 15. | Harry Hiltner | 213 | 1991 | 1952-1955 | |
| 16. | Alonzo Parisi | 200 | 1461 | 1952-1955 | |
| 17. | Leo Kozlowski | 173 | 958 | 1952-1955 | |
| 18. | Pete Rustin | 163 | 1049 | 1952-1955 | |
| 19. | Richard Little | 161 | 997 | 1952-1955 | |
| 20. | Eldridge Lane | 157 | 1069 | 1952-1955 | |
| 21. | Bobby Jeppesen | 143 | 609 | 1952-1954 | |
| 22. | Tim Wilkens | 142 | 1398 | 1952-1955 | |
| 23. | Emerson Freer | 133 | 720 | 1952-1955 | |
| 24. | Guillermo Castillo | 123 | 889 | 1953-1954 | |
| 25. | Dale Hirsch | 118 | 595 | 1953-1955 | |
| 26. | Bill Brier | 116 | 577 | 1952-1955 | |
| 27. | Robert Neal | 94 | 461 | 1952-1952 | |
| 28. | Daniel Rowell | 88 | 1106 | 1953-1955 | |
| 29. | Alberto Villar | 75 | 470 | 1952-1952 | |
| 30. | Keith Hinton | 73 | 388 | 1954-1955 | |
| 31. | Steven Harper | 70 | 481 | 1952-1955 | |
| 32. | Matthew Foulk | 66 | 379 | 1952-1954 | |
| 33. | Victor Espinoza | 62 | 482 | 1954-1955 | |
| 34. | Ian Dennard | 53 | 239 | 1955-1955 | |
| 35. | George Sanchez | 33 | 172 | 1952-1952 | |
| 36. | Jason Herrera | 31 | 179 | 1954-1955 | |
| 37. | Alex Plasencia | 30 | 181 | 1952-1953 | |
| 38. | Gregory Hanna | 28 | 188 | 1953-1955 | |
| 39. | David Hindman | 27 | 214 | 1955-1955 | |
| Cody Morris | 27 | 179 | 1955-1955 | ||
| John Thomas | 27 | 126 | 1952-1953 | ||
| 42. | Jason Johnson | 20 | 139 | 1952-1952 | |
| 43. | Howard Stull | 18 | 72 | 1952-1953 | |
| 44. | Paul Huskey | 16 | 71 | 1952-1952 | |
| 45. | Bobby Singleton | 14 | 43 | 1953-1954 | |
| 46. | Troy Graham | 12 | 117 | 1954-1955 | |
| 47. | Thomas McCarthy | 11 | 80 | 1954-1955 | |
| 48. | John Kohut | 7 | 51 | 1953-1954 | |
| 49. | Stanton Garfinkel | 3 | 9 | 1955-1955 | |
| 50. | David Cooper | 2 | 15 | 1952-1953 | |
| Curtis Wallner | 2 | 4 | 1953-1953 |
| For questions or to report errors, please send us a note. |