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| Center Fielders Career Strikeouts Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Strikeouts | PA | Years | Single Season Leaderboard |
| 1. | Michael Van Pelt | 313 | 1971 | 1952-1955 | |
| 2. | John Lafortune | 301 | 2341 | 1952-1955 | |
| 3. | Derek Zurita | 290 | 2413 | 1952-1955 | |
| 4. | Arnold Keener | 289 | 2317 | 1952-1955 | |
| 5. | Andrew Goodwyn | 285 | 1642 | 1952-1955 | |
| 6. | John Heaps | 270 | 2348 | 1952-1955 | |
| 7. | Ronald Haefner | 269 | 1531 | 1952-1955 | |
| 8. | Tony Flores | 255 | 2324 | 1952-1955 | |
| 9. | Ryan Normand | 248 | 1608 | 1953-1955 | |
| 10. | Abraham Chee | 245 | 2338 | 1952-1955 | |
| 11. | Timothy Johnson | 236 | 1995 | 1952-1955 | |
| 12. | Christian Carpenter | 233 | 2322 | 1952-1955 | |
| Ray Teske | 233 | 1861 | 1952-1955 | ||
| Marlin Lett | 233 | 1708 | 1952-1955 | ||
| 15. | Gerald Johnson | 224 | 2111 | 1952-1955 | |
| 16. | William Fraley | 215 | 1223 | 1952-1955 | |
| 17. | Pedro Savino | 212 | 2297 | 1952-1955 | |
| 18. | Louis Shouse | 209 | 1836 | 1952-1955 | |
| 19. | Gene Dones | 202 | 879 | 1952-1954 | |
| 20. | Curtis Folden | 198 | 1070 | 1952-1954 | |
| 21. | Leroy McKenzie | 190 | 2091 | 1952-1955 | |
| 22. | Rodney Martone | 186 | 1533 | 1952-1955 | |
| 23. | Jonathan Mulder | 179 | 791 | 1952-1954 | |
| 24. | Manny Anguita | 176 | 1764 | 1952-1955 | |
| 25. | James Fabela | 171 | 1443 | 1953-1955 | |
| 26. | James Zaleski | 169 | 823 | 1952-1954 | |
| 27. | Brandon Fowler | 164 | 830 | 1952-1955 | |
| 28. | James Fegan | 163 | 856 | 1952-1955 | |
| 29. | Jacob Cuthbert | 159 | 1354 | 1953-1955 | |
| Tyler Galentine | 159 | 1247 | 1952-1955 | ||
| 31. | Roger Morrell | 158 | 817 | 1952-1955 | |
| 32. | Carlos Duque | 148 | 787 | 1952-1955 | |
| 33. | David Colucci | 147 | 1317 | 1952-1955 | |
| 34. | John Ayers | 132 | 638 | 1952-1955 | |
| 35. | Peter Elizalde | 121 | 625 | 1953-1955 | |
| 36. | Randy Nieto | 115 | 718 | 1952-1954 | |
| 37. | Robert Staub | 107 | 540 | 1952-1952 | |
| 38. | Joseph Mraz | 98 | 615 | 1953-1955 | |
| 39. | Chris Caton | 94 | 461 | 1952-1955 | |
| 40. | Jason Massingill | 82 | 504 | 1954-1955 | |
| 41. | Miguel Santa | 76 | 482 | 1952-1955 | |
| 42. | David Wood | 72 | 579 | 1952-1954 | |
| 43. | Andrew Benard | 65 | 329 | 1954-1955 | |
| 44. | David Gaiter | 64 | 453 | 1952-1955 | |
| 45. | Todd Borkowski | 61 | 417 | 1952-1955 | |
| 46. | Mark Sermons | 60 | 211 | 1954-1954 | |
| 47. | Donald Crook | 52 | 292 | 1952-1953 | |
| 48. | Jason McCoy | 51 | 283 | 1952-1955 | |
| 49. | Chad Furst | 47 | 391 | 1952-1952 | |
| 50. | Lynn Clontz | 35 | 192 | 1955-1955 | |
| 51. | Andrew Laforest | 34 | 148 | 1952-1955 | |
| 52. | Richard Walker | 33 | 273 | 1952-1955 | |
| Deangelo Cervantes | 33 | 173 | 1952-1952 | ||
| 54. | Edward Hopwood | 30 | 198 | 1953-1955 | |
| Neil Magill | 30 | 175 | 1952-1952 | ||
| 56. | Robert Collins | 25 | 194 | 1954-1955 | |
| 57. | Dustin Zellner | 24 | 254 | 1952-1955 | |
| 58. | John Brooks | 22 | 93 | 1954-1954 | |
| 59. | Rodney Boehmer | 21 | 130 | 1954-1955 | |
| 60. | Eric Ferrill | 19 | 118 | 1953-1953 | |
| 61. | Franklyn Tumlin | 12 | 71 | 1952-1952 | |
| Robert Owen | 12 | 61 | 1952-1952 | ||
| 63. | Devon Burcham | 8 | 46 | 1954-1954 | |
| 64. | Curtis Deacon | 7 | 23 | 1955-1955 | |
| Paul Millman | 7 | 22 | 1953-1954 | ||
| 66. | Donald Windham | 5 | 23 | 1952-1952 | |
| 67. | Dean Govea | 3 | 15 | 1955-1955 | |
| Fred Carswell | 3 | 33 | 1952-1952 | ||
| 69. | Jeffery Engelman | 2 | 27 | 1952-1954 |
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