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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Álex González# | 132 | 2011-2014 | |
| 2 | Craig Brown | 122 | 1969-1976 | |
| 3 | Jesús López# | 121 | 2009-2014 | |
| 4 | Michael Berry | 115 | 1969-1981 | |
| 5 | Mario Guerra | 103 | 1995-2005 | |
| 6 | José Altamar# | 99 | 2009-2014 | |
| 7 | Miguel Salinas# | 96 | 2007-2011 | |
| 8 | Sherwood Gilbert | 94 | 1995-2002 | |
| 9 | Roberto González# | 93 | 2009-2014 | |
| 10 | António Násquez | 89 | 1993-2005 | |
| 11 | Paul Hamilton | 87 | 1996-2008 | |
| 12 | Harry Bishop# | 86 | 2009-2014 | |
| 13 | Nick Salm# | 85 | 2007-2014 | |
| 13 | Ricardo Velásquez | 85 | 1971-1985 | |
| 15 | Pancho Villalobos | 83 | 1995-2003 | |
| 16 | Gomes Taboada# | 82 | 2006-2013 | |
| 17 | Charles Walker | 81 | 1970-1980 | |
| 18 | Gilberto Flores | 80 | 1992-2001 | |
| 18 | Greg Montgomery# | 80 | 2011-2014 | |
| 20 | José Burra | 76 | 1964-1973 | |
| 21 | Michael Lewis# | 75 | 2004-2007 | |
| 22 | Floyd Petersen | 74 | 1994-2000 | |
| 22 | Claudio Vargas# | 74 | 2006-2012 | |
| 24 | José López# | 73 | 2000-2013 | |
| 24 | Kevin Noble# | 73 | 2010-2014 | |
| 26 | Chris Glenn# | 72 | 2006-2014 | |
| 27 | David Cavilla | 71 | 2008-2014 | |
| 27 | António Cruz | 71 | 1987-1991 | |
| 29 | Steve Johnson# | 70 | 2009-2014 | |
| 30 | Stan Evans# | 69 | 2009-2014 | |
| 30 | Juan Gabriel# | 69 | 1999-2005 | |
| 30 | Garry Robinson | 69 | 1970-1974 | |
| 33 | Larry Hines | 67 | 1981-1986 | |
| 33 | Bert Larson# | 67 | 2001-2007 | |
| 35 | Jeff Jones | 66 | 1997-2007 | |
| 35 | Brian Vélez# | 66 | 2011-2014 | |
| 37 | Alejandro Castillo | 65 | 1984-1990 | |
| 37 | Ángel Díaz | 65 | 2001-2005 | |
| 37 | Justin Sims# | 65 | 2009-2013 | |
| 40 | Harry Christensen | 64 | 1991-2005 | |
| 40 | Rogelio Lemus# | 64 | 2011-2014 | |
| 40 | Jim Morris | 64 | 1989-1991 | |
| 40 | Sammy Robinson# | 64 | 2009-2014 | |
| 40 | Orlando Sánchez | 64 | 2005-2009 | |
| 40 | Roy Wright# | 64 | 2008-2014 | |
| 46 | Murray Gallagher | 63 | 1992-2004 | |
| 46 | Joaquín Gines | 63 | 1992-1994 | |
| 46 | Manuel Gutiérrez# | 63 | 2010-2013 | |
| 49 | Carl Aragón | 62 | 1996-1998 | |
| 49 | Jonathan Collins | 62 | 1969-1977 | |
| 49 | Bernaldyn Lavado | 62 | 1967-1976 | |
| 49 | Rafael Ruíz# | 62 | 2011-2013 | |
| 49 | Tomas Solis | 62 | 1958-1967 | |
| 49 | Juan Valentín# | 62 | 2011-2014 | |
| 55 | Paul Ellis | 61 | 2003-2010 | |
| 55 | Fernando Sardiña# | 61 | 2005-2010 | |
| 57 | Max Barton | 60 | 1999-2006 | |
| 57 | Miguel Angel Bojórquez | 60 | 1965-1969 | |
| 57 | Sean Cain | 60 | 1990-1998 | |
| 57 | Lucas Hatton | 60 | 2003-2007 | |
| 57 | Stephen Sanders | 60 | 1975-1981 | |
| 62 | Tomás Ibarra# | 59 | 2009-2014 | |
| 62 | Carlos Padilla# | 59 | 2000-2014 | |
| 62 | Zheng-xin Tow | 59 | 1970-1979 | |
| 65 | Aurelio Galindo | 58 | 1972-1976 | |
| 65 | Bob King | 58 | 1991-1994 | |
| 65 | Ze-min Wang | 58 | 1992-1998 | |
| 68 | Arthur Adams# | 57 | 2009-2014 | |
| 68 | Luis Cantú# | 57 | 2008-2014 | |
| 68 | Jody Lewis | 57 | 1975-1981 | |
| 68 | Joaquín López# | 57 | 2012-2014 | |
| 68 | José Matos | 57 | 2006-2012 | |
| 68 | Chris Olivarez# | 57 | 2008-2014 | |
| 68 | Luis Reynoso | 57 | 1965-1969 | |
| 68 | Brian Roberts | 57 | 1996-2006 | |
| 76 | Flynn Carter | 56 | 1997-2003 | |
| 76 | Hugh Domínguez# | 56 | 2010-2014 | |
| 76 | Brandon Giles | 56 | 1962-1975 | |
| 76 | Rodrigo Ávila | 56 | 1997-1999 | |
| 80 | Kevin Cummins | 55 | 1964-1968 | |
| 80 | William Martin# | 55 | 2008-2011 | |
| 80 | Trevor Mason | 55 | 1973-1977 | |
| 80 | Juan Solís | 55 | 1968-1973 | |
| 84 | Kade Brady | 54 | 1996-1999 | |
| 84 | Félix Cruz | 54 | 1963-1972 | |
| 84 | Keith Haney | 54 | 1996-2006 | |
| 84 | Mario López | 54 | 1984-1987 | |
| 88 | Vicente Calderón# | 53 | 2013-2014 | |
| 88 | John Coleman# | 53 | 2007-2011 | |
| 88 | Joey Ellis | 53 | 1969-1980 | |
| 88 | Pedro Icaza# | 53 | 2009-2014 | |
| 92 | Ernie Barber | 52 | 1998-2004 | |
| 92 | Jesús Cardenas# | 52 | 2001-2010 | |
| 92 | Van Gunther | 52 | 1970-1981 | |
| 92 | John Hicks | 52 | 1987-1996 | |
| 92 | Josh Mitchell# | 52 | 2010-2012 | |
| 92 | Mario Morales | 52 | 2000-2008 | |
| 98 | Broderick LeBlanc# | 51 | 2006-2009 | |
| 98 | Javier Rojas# | 51 | 2011-2014 | |
| 98 | Michael Stroud# | 51 | 2010-2014 |
