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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | RBI | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Andrew Hardy | 406 | 1959-1973 | |
| 2 | Raúl Otero | 382 | 1960-1974 | |
| 3 | Lou Rosário | 373 | 1996-2004 | |
| 4 | Lee McClendon | 310 | 1988-1994 | |
| 5 | Ramón Ruíz | 288 | 2002-2007 | |
| 6 | Ray Hebert | 273 | 1982-1992 | |
| 7 | Andrew Williams | 271 | 1958-1962 | |
| 8 | Fred Thompson | 270 | 1970-1976 | |
| 9 | George MacQuey | 269 | 1997-2007 | |
| 10 | Jeffery Taylor | 265 | 1999-2004 | |
| 11 | Carlos Reyna | 264 | 2001-2005 | |
| 12 | Kenny Viccars# | 263 | 2000-2004 | |
| 13 | Ryan Schneider | 259 | 1968-1973 | |
| 14 | José Montaño | 253 | 1982-1986 | |
| 15 | Jorge Medrano | 246 | 1984-1997 | |
| 16 | David Pratt | 243 | 1967-1971 | |
| 17 | Scott Rogers | 242 | 1984-1995 | |
| 18 | Damián Castellanos | 235 | 2003-2013 | |
| 18 | Jack Greene | 235 | 1966-1980 | |
| 18 | Josh Miller | 235 | 1974-1990 | |
| 21 | Willard Sharma | 232 | 1957-1965 | |
| 22 | Terry Faris | 231 | 1957-1960 | |
| 22 | Gordon Tapia | 231 | 1998-2008 | |
| 24 | Gary Burris | 229 | 1972-1981 | |
| 25 | Glenn Moore | 228 | 1972-1976 | |
| 26 | John Horton | 224 | 1997-2001 | |
| 27 | Tomás Pérez | 217 | 1973-1985 | |
| 28 | Hak-su Yi | 216 | 2003-2008 | |
| 29 | Ethan Widener | 215 | 2005-2010 | |
| 30 | Don Brown | 214 | 1999-2014 | |
| 31 | Gabriel Jaramillo# | 213 | 2002-2005 | |
| 32 | Anthony Kinch | 211 | 1987-1991 | |
| 33 | Morgan MacKinney | 209 | 1970-1987 | |
| 33 | Robert Sullivan | 209 | 1973-1978 | |
| 35 | Pedro Cabaña | 208 | 1957-1965 | |
| 35 | Carlos Rivas | 208 | 1980-1986 | |
| 37 | Jacob Busch | 206 | 1957-1959 | |
| 37 | Pedro Castillo | 206 | 1988-1993 | |
| 37 | Tim Lucas# | 206 | 2013-2015 | |
| 37 | Pedro Manuel | 206 | 1996-2010 | |
| 37 | Paul Wells | 206 | 1973-1982 | |
| 42 | Clint Lake | 205 | 1971-1975 | |
| 42 | Tom Smith | 205 | 1974-1984 | |
| 42 | Chris Warner# | 205 | 2009-2015 | |
| 45 | Luis Garza | 204 | 1974-1976 | |
| 45 | Tom Porter | 204 | 1961-1965 | |
| 47 | Alex Bailey# | 202 | 2000-2004 | |
| 47 | Roberto Castaneda# | 202 | 2003-2014 | |
| 47 | José Ramírez | 202 | 1971-1975 | |
| 50 | António González# | 201 | 2002-2014 | |
| 51 | Oliver Frazier | 200 | 1981-1984 | |
| 51 | Jeremy LaFreniere | 200 | 1997-2001 | |
| 51 | Miguel Mata | 200 | 2003-2013 | |
| 54 | Rickey Wade | 199 | 1979-1990 | |
| 55 | Leslie Hires | 198 | 1957-1960 | |
| 55 | José Jurado | 198 | 1972-1981 | |
| 57 | Juan Delgado | 197 | 1962-1967 | |
| 57 | Carlos Hernández# | 197 | 2006-2011 | |
| 57 | Jim Love# | 197 | 2004-2008 | |
| 60 | Guy White# | 196 | 2008-2015 | |
| 61 | Allan Murphy | 192 | 1996-2005 | |
| 62 | Ed Gamble | 191 | 1998-2011 | |
| 63 | Stanford Cates | 190 | 1996-2000 | |
| 63 | Mike Clark | 190 | 1970-1981 | |
| 65 | Juan Castillo | 189 | 1962-1976 | |
| 65 | Neil Guillén# | 189 | 1998-2001 | |
| 65 | José Martínez | 189 | 2001-2006 | |
| 65 | Bill Scott | 189 | 1988-2002 | |
| 69 | Shigemori Hirano | 188 | 1976-1980 | |
| 70 | Luis Cuellar# | 187 | 2013-2015 | |
| 70 | Francisco Solís | 187 | 2001-2005 | |
| 72 | José Palácios | 186 | 1999-2012 | |
| 72 | Sam Samways | 186 | 1979-1983 | |
| 74 | Xavier Bartlett | 185 | 1997-2004 | |
| 74 | Paul Charon | 185 | 1957-1960 | |
| 74 | Aurelio Martínez# | 185 | 2011-2015 | |
| 77 | Alec Adams | 184 | 1966-1973 | |
| 77 | Ramón Alemán | 184 | 1994-2008 | |
| 79 | Richard Báez# | 183 | 2001-2015 | |
| 79 | William McClendon | 183 | 1983-1988 | |
| 81 | Willard Hart | 182 | 1998-2003 | |
| 81 | Patrick Knight | 182 | 1994-2001 | |
| 81 | Ricardo Moreno | 182 | 2005-2008 | |
| 84 | Manuel Pérez | 181 | 1984-1988 | |
| 85 | Alejandro Olivares | 180 | 1959-1969 | |
| 86 | Steve Bass | 179 | 1973-1976 | |
| 86 | John Cantrell | 179 | 1994-1998 | |
| 88 | Nathan Clark | 176 | 1960-1962 | |
| 89 | Marcos Féliz | 175 | 1993-1997 | |
| 89 | Javier Molina | 175 | 1996-2000 | |
| 89 | Bob Rogers | 175 | 1985-1993 | |
| 89 | Roberto Rosales# | 175 | 2008-2013 | |
| 89 | Jesse Sampson | 175 | 1979-1993 | |
| 94 | John Ayers | 174 | 1975-1980 | |
| 94 | Francisco López# | 174 | 2001-2004 | |
| 96 | Mike Hunt | 173 | 1992-2002 | |
| 96 | Ken Jackson# | 173 | 2008-2015 | |
| 98 | Jeff Davies | 172 | 1977-1984 | |
| 99 | Diego González | 171 | 1966-1981 | |
| 100 | Jeffery Astudillo | 170 | 1957-1963 |
