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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Chris Ward | 216 | 1995-2006 | |
| 2 | Francisco Ramírez# | 181 | 2010-2015 | |
| 3 | Armando Mendoza | 123 | 1972-1978 | |
| 4 | Wes Shepard | 107 | 1989-1992 | |
| 5 | Esteban Castillo | 106 | 1971-1980 | |
| 6 | Juan Valadez | 103 | 1974-1976 | |
| 7 | Xavier Bartlett | 98 | 2000-2005 | |
| 8 | Ernesto Luna | 92 | 2010-2014 | |
| 9 | Paul Knowles# | 91 | 2012-2015 | |
| 10 | Francisco González | 89 | 2004-2012 | |
| 11 | Roberto Méndez | 85 | 1977-1998 | |
| 12 | Matt Miller | 82 | 1977-1988 | |
| 13 | Pedro Castillo | 78 | 1993-2003 | |
| 13 | José Márquez | 78 | 1987-1996 | |
| 15 | Hamilton MacGilchrist | 76 | 1983-1990 | |
| 16 | Luis Cavezón | 72 | 1980-1989 | |
| 17 | Ray King | 71 | 1979-1986 | |
| 18 | Dan Carter | 70 | 1993-1995 | |
| 18 | Abel White | 70 | 1970-1972 | |
| 20 | Héctor Rodríguez | 69 | 2003-2008 | |
| 21 | Alfonso Vásquez | 68 | 1990-1995 | |
| 22 | James Cogswell | 67 | 1978-1982 | |
| 22 | Lee Huggins | 67 | 1987-1999 | |
| 22 | Sam Patterson | 67 | 1969-1972 | |
| 25 | Darrell Long | 65 | 1986-1987 | |
| 25 | Pedro Maes# | 65 | 2009-2015 | |
| 25 | Derek Moss | 65 | 1963-1965 | |
| 28 | Jonathan Moore | 63 | 1983-1985 | |
| 28 | Jerry Myers | 63 | 1981-1987 | |
| 30 | José Salinas# | 62 | 2000-2002 | |
| 30 | Gordon Tapia | 62 | 2002-2007 | |
| 32 | Luis Cruz | 61 | 1999-2006 | |
| 32 | Martín Ruedas | 61 | 1996-1998 | |
| 34 | Miguel Martínez | 60 | 1998-2009 | |
| 34 | Tommy Rogers# | 60 | 2012-2013 | |
| 36 | James Brown | 59 | 1963-1974 | |
| 36 | Jorge Eseinosa | 59 | 1980-1991 | |
| 36 | José Medina | 59 | 1999-2007 | |
| 36 | Paul Moore | 59 | 1998-2005 | |
| 36 | Kyle Morris | 59 | 1993-2003 | |
| 36 | Luis Orozco | 59 | 1991-1996 | |
| 36 | Jeff Rodríguez | 59 | 1998-2004 | |
| 36 | Justin Washington | 59 | 1987-1989 | |
| 36 | Fred Watkins | 59 | 1995-2002 | |
| 45 | Bob Jackson | 58 | 1986-1988 | |
| 45 | Edgar Miller# | 58 | 2012-2015 | |
| 45 | Jerry Price# | 58 | 2012-2015 | |
| 48 | Francisco Aranda | 57 | 1968-1971 | |
| 48 | Vicente Gallegos | 57 | 1987-1999 | |
| 48 | Robert Jackson | 57 | 1971-1980 | |
| 48 | Jeremy Powers | 57 | 1972-1986 | |
| 48 | Guillermo Soto | 57 | 2003-2009 | |
| 53 | Jacob Mullins | 56 | 1957-1962 | |
| 53 | Javier Sánchez | 56 | 2003-2006 | |
| 55 | Alberto Cervantes | 55 | 2004-2007 | |
| 55 | Luis Guevara | 55 | 1977-1987 | |
| 55 | Francisco Rey | 55 | 1967-1969 | |
| 55 | Bill Scott | 55 | 1994-2003 | |
| 59 | Shannon Chamberlain | 54 | 1974-1976 | |
| 59 | Michael García | 54 | 1987-1989 | |
| 59 | Lee McClendon | 54 | 1994-1995 | |
| 59 | Wayne Smith | 54 | 1960-1970 | |
| 63 | Carlos Gómez# | 53 | 2008-2012 | |
| 63 | Brad Mayer | 53 | 1997-2007 | |
| 63 | Mal McGinnis | 53 | 1977-1978 | |
| 63 | Rafael Pagán | 53 | 2003-2005 | |
| 63 | Chris Poe# | 53 | 2010-2014 | |
| 63 | Jake Thomas | 53 | 2000-2013 | |
| 63 | Ricardo Visuna | 53 | 1994-1997 | |
| 70 | Eduardo Correa | 52 | 1982-1988 | |
| 70 | António Rodríguez# | 52 | 2014-2015 | |
| 70 | Tom Wood | 52 | 1989-1992 | |
| 73 | Todd Armstead | 51 | 1988-2000 | |
| 73 | Brandon Barraclough | 51 | 2005-2011 | |
| 73 | Marcel Fauteux | 51 | 1998-1999 | |
| 73 | Randy Forrest# | 51 | 2005-2015 | |
| 73 | Pablo Féliz | 51 | 2001-2009 | |
| 73 | Lee Nixon | 51 | 1981-1983 | |
| 73 | Craig Randall | 51 | 1995-2000 | |
| 73 | Michael Spiegle | 51 | 1991-2004 | |
| 81 | Mark Bonfield | 50 | 1977-1978 | |
| 81 | Dave Cox | 50 | 1994-1998 | |
| 81 | Manuel Gómez | 50 | 2004-2014 | |
| 81 | Duane Hill# | 50 | 2014-2015 | |
| 81 | Dan Joseph | 50 | 2003-2007 | |
| 86 | José Antonio | 49 | 1990-1991 | |
| 86 | Tim Brown# | 49 | 2006-2014 | |
| 86 | Mike Clark | 49 | 1974-1981 | |
| 86 | Ken Delgado | 49 | 1993-2000 | |
| 86 | Alberto Díaz | 49 | 2001-2004 | |
| 86 | Júlio Díaz | 49 | 2000-2009 | |
| 86 | Brian Evans | 49 | 1978-1983 | |
| 86 | Vaughn Green | 49 | 1957-1962 | |
| 86 | Shigemori Hirano | 49 | 1980-1982 | |
| 86 | Armando Rivera | 49 | 1972-1986 | |
| 86 | Ronald Steck | 49 | 1965-1977 | |
| 97 | Bruce Bruce | 48 | 1972-1986 | |
| 97 | Roberto García | 48 | 1969-1977 | |
| 97 | Mike Martin | 48 | 1997-2005 | |
| 97 | José Ortíz | 48 | 1972-1982 |
