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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Craig Brown | 122 | 1969-1976 | |
| 2 | Jesús López# | 121 | 2009-2014 | |
| 3 | Michael Berry | 115 | 1969-1981 | |
| 4 | Mario Guerra | 103 | 1995-2005 | |
| 5 | Álex González# | 98 | 2011-2014 | |
| 6 | Miguel Salinas# | 96 | 2007-2011 | |
| 7 | Sherwood Gilbert | 94 | 1995-2002 | |
| 8 | José Altamar# | 91 | 2009-2014 | |
| 9 | Roberto González# | 89 | 2009-2014 | |
| 9 | António Násquez | 89 | 1993-2005 | |
| 11 | William MacCaishe# | 88 | 2007-2012 | |
| 12 | Paul Hamilton | 87 | 1996-2008 | |
| 13 | Ricardo Velásquez | 85 | 1971-1985 | |
| 14 | Pancho Villalobos | 83 | 1995-2003 | |
| 15 | Gomes Taboada# | 82 | 2006-2013 | |
| 16 | Charles Walker | 81 | 1970-1980 | |
| 17 | Gilberto Flores | 80 | 1992-2001 | |
| 18 | José Burra | 76 | 1964-1973 | |
| 19 | Michael Lewis# | 75 | 2004-2007 | |
| 20 | Floyd Petersen | 74 | 1994-2000 | |
| 20 | Claudio Vargas# | 74 | 2006-2012 | |
| 22 | José López# | 73 | 2000-2013 | |
| 22 | Nick Salm# | 73 | 2007-2014 | |
| 22 | António Vargas# | 73 | 2003-2009 | |
| 25 | Harry Bishop# | 72 | 2009-2014 | |
| 26 | António Cruz | 71 | 1987-1991 | |
| 27 | Juan Gabriel# | 69 | 1999-2005 | |
| 27 | Garry Robinson | 69 | 1970-1974 | |
| 29 | Steve Ferguson# | 67 | 2008-2013 | |
| 29 | Larry Hines | 67 | 1981-1986 | |
| 29 | Bert Larson# | 67 | 2001-2007 | |
| 32 | Jeff Jones | 66 | 1997-2007 | |
| 33 | Alejandro Castillo | 65 | 1984-1990 | |
| 33 | Ángel Díaz | 65 | 2001-2005 | |
| 33 | Justin Sims# | 65 | 2009-2013 | |
| 36 | Harry Christensen | 64 | 1991-2005 | |
| 36 | Jim Morris | 64 | 1989-1991 | |
| 36 | Orlando Sánchez | 64 | 2005-2009 | |
| 39 | Murray Gallagher | 63 | 1992-2004 | |
| 39 | Joaquín Gines | 63 | 1992-1994 | |
| 39 | Manuel Gutiérrez# | 63 | 2010-2013 | |
| 42 | Carl Aragón | 62 | 1996-1998 | |
| 42 | Jonathan Collins | 62 | 1969-1977 | |
| 42 | Bernaldyn Lavado | 62 | 1967-1976 | |
| 42 | Greg Montgomery# | 62 | 2011-2014 | |
| 42 | Rafael Ruíz# | 62 | 2011-2013 | |
| 42 | Tomas Solis | 62 | 1958-1967 | |
| 48 | David Cavilla# | 61 | 2008-2014 | |
| 48 | Paul Ellis | 61 | 2003-2010 | |
| 48 | Steve Johnson# | 61 | 2009-2014 | |
| 48 | Fernando Sardiña# | 61 | 2005-2010 | |
| 52 | Max Barton | 60 | 1999-2006 | |
| 52 | Miguel Angel Bojórquez | 60 | 1965-1969 | |
| 52 | Sean Cain | 60 | 1990-1998 | |
| 52 | Chris Glenn# | 60 | 2006-2014 | |
| 52 | Lucas Hatton# | 60 | 2003-2007 | |
| 52 | Juan Peña# | 60 | 2011-2013 | |
| 52 | Stephen Sanders | 60 | 1975-1981 | |
| 59 | Stan Evans# | 59 | 2009-2014 | |
| 59 | Tomás Ibarra# | 59 | 2009-2014 | |
| 59 | Zheng-xin Tow | 59 | 1970-1979 | |
| 62 | Aurelio Galindo | 58 | 1972-1976 | |
| 62 | Bob King | 58 | 1991-1994 | |
| 62 | Carlos Padilla# | 58 | 2000-2008 | |
| 62 | Ze-min Wang | 58 | 1992-1998 | |
| 66 | Jody Lewis | 57 | 1975-1981 | |
| 66 | José Matos | 57 | 2006-2012 | |
| 66 | Chris Olivarez# | 57 | 2008-2013 | |
| 66 | Luis Reynoso | 57 | 1965-1969 | |
| 66 | Brian Roberts | 57 | 1996-2006 | |
| 71 | Flynn Carter | 56 | 1997-2003 | |
| 71 | Brandon Giles | 56 | 1962-1975 | |
| 71 | Rodrigo Ávila | 56 | 1997-1999 | |
| 74 | Kevin Cummins | 55 | 1964-1968 | |
| 74 | William Martin# | 55 | 2008-2011 | |
| 74 | Trevor Mason | 55 | 1973-1977 | |
| 74 | Juan Solís | 55 | 1968-1973 | |
| 78 | Kade Brady# | 54 | 1996-1999 | |
| 78 | Luis Cantú# | 54 | 2008-2014 | |
| 78 | Félix Cruz | 54 | 1963-1972 | |
| 78 | Keith Haney | 54 | 1996-2006 | |
| 78 | Mario López | 54 | 1984-1987 | |
| 83 | John Coleman# | 53 | 2007-2011 | |
| 83 | Joey Ellis | 53 | 1969-1980 | |
| 83 | Carlos Gallegos# | 53 | 2007-2013 | |
| 83 | Rogelio Lemus# | 53 | 2011-2014 | |
| 87 | Arthur Adams# | 52 | 2009-2014 | |
| 87 | Ernie Barber | 52 | 1998-2004 | |
| 87 | Jesús Cardenas# | 52 | 2001-2010 | |
| 87 | Van Gunther | 52 | 1970-1981 | |
| 87 | John Hicks | 52 | 1987-1996 | |
| 87 | Josh Mitchell# | 52 | 2010-2012 | |
| 87 | Mario Morales | 52 | 2000-2008 | |
| 87 | Roy Wright# | 52 | 2008-2014 | |
| 95 | Broderick LeBlanc# | 51 | 2006-2009 | |
| 95 | Brian Vélez# | 51 | 2011-2014 | |
| 97 | Hugh Domínguez# | 50 | 2010-2014 | |
| 97 | Edward Hockenberry# | 50 | 2003-2007 | |
| 97 | Brent House# | 50 | 2003-2005 | |
| 97 | Pedro Icaza# | 50 | 2009-2014 |
