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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Dean Campanelli | 479 | 1960-1971 | |
| 2 | Jesús Escobar | 449 | 1992-2007 | |
| 3 | Dwayne Johnson* | 415 | 1987-2004 | |
| 4 | Dan Gorst* | 316 | 1977-1993 | |
| 5 | Denver Dean* | 297 | 1984-1997 | |
| 6 | Derek Fisher | 295 | 1967-1977 | |
| 7 | Guillermo De Los Santos | 289 | 1980-1996 | |
| 8 | Pedro Vélez | 246 | 1962-1979 | |
| 9 | David Banks | 243 | 1980-1990 | |
| 10 | Félix Ferrer | 240 | 1986-1999 | |
| 11 | John Sweeney | 236 | 1965-1976 | |
| 12 | Mark Bates | 230 | 1964-1977 | |
| 13 | Evan Walters | 227 | 1976-1989 | |
| 14 | Jack Brown | 223 | 1977-1988 | |
| 14 | Norm Jones | 223 | 1963-1981 | |
| 16 | Eric Ehlers | 219 | 1961-1976 | |
| 17 | Kevin Caldwell | 216 | 1969-1981 | |
| 18 | Alfonso Haya | 213 | 1963-1972 | |
| 19 | Pedro Rivera | 210 | 1982-1995 | |
| 20 | Esteban Gonzáles | 207 | 1995-2005 | |
| 21 | Jeff Bruce# | 205 | 2004-2014 | |
| 22 | Allen Mueller | 204 | 1973-1989 | |
| 23 | Ricardo Benítez | 203 | 1967-1979 | |
| 24 | Sergio Tavárez | 198 | 2000-2012 | |
| 25 | Matt Oster# | 194 | 2004-2014 | |
| 26 | Artie Burton | 193 | 1992-2004 | |
| 27 | Cullen Moore | 192 | 1964-1978 | |
| 28 | Kent Izzard | 184 | 1962-1978 | |
| 29 | Troy Hart | 183 | 1992-2005 | |
| 30 | Roberto Hinojosa | 181 | 1995-2005 | |
| 31 | Stu Miller | 179 | 1980-1995 | |
| 32 | Brit White | 175 | 1979-1992 | |
| 33 | Júlio García | 173 | 1965-1974 | |
| 34 | Gabe Davis | 169 | 1973-1988 | |
| 35 | Matt Huddy | 168 | 1987-2000 | |
| 36 | Sancho Mendoza | 165 | 1966-1978 | |
| 37 | Derrek Stevens# | 164 | 2004-2014 | |
| 38 | Carlos Mora# | 162 | 2002-2014 | |
| 38 | Ken Serrano | 162 | 1982-1996 | |
| 40 | Marvin Miller | 157 | 1997-2010 | |
| 41 | Bill Eccles | 155 | 1981-1990 | |
| 42 | Juan Meléndez | 150 | 1980-1997 | |
| 43 | Joe Flannery | 148 | 1981-1992 | |
| 43 | Juan Ruíz | 148 | 1989-2002 | |
| 45 | Jeff Sánchez | 146 | 1992-2005 | |
| 46 | Juan Jiménez | 143 | 1994-2006 | |
| 47 | Patrick O'Higgins | 138 | 1974-1985 | |
| 48 | Billy Sheehan | 137 | 1968-1985 | |
| 49 | Jim Walker | 136 | 1966-1973 | |
| 50 | Tim Kirkpatrick# | 134 | 1999-2013 | |
| 51 | Brad Norwood | 132 | 1975-1984 | |
| 52 | Yu-wei Su-Tu | 130 | 1968-1981 | |
| 52 | David Wilson | 130 | 1966-1976 | |
| 54 | Adam Mire | 129 | 1954-1965 | |
| 55 | Adrian Smith | 126 | 1952-1965 | |
| 56 | Nelson Butler | 122 | 2000-2010 | |
| 57 | Miguel Luna# | 121 | 2003-2014 | |
| 58 | Eric Porter | 119 | 1998-2010 | |
| 59 | Lúcio Martínez | 115 | 1967-1981 | |
| 60 | Cornell Wiggins | 113 | 1987-1992 | |
| 61 | Carlos Gonzáles | 111 | 1993-2005 | |
| 62 | Rob Crawford | 110 | 1992-2003 | |
| 63 | Carlos Medina | 109 | 1979-1989 | |
| 64 | Howard Gibbons | 108 | 1993-2003 | |
| 65 | Andrés Ramírez | 105 | 1978-1983 | |
| 65 | Jeffrey Sweeney | 105 | 1973-1981 | |
| 67 | Kenzaburo Ageda | 104 | 1992-2003 | |
| 68 | Dan Anderson | 103 | 1990-2001 | |
| 69 | Mauro Acevedo | 102 | 2003-2009 | |
| 69 | Júlio Berrones | 102 | 1987-1997 | |
| 71 | Pat Piper | 101 | 1985-2002 | |
| 72 | Amos Moore | 99 | 1964-1973 | |
| 73 | Tim McCauley | 96 | 1983-1998 | |
| 74 | Garrett Wood | 93 | 1954-1966 | |
| 75 | Domingo Contreras# | 91 | 2007-2014 | |
| 76 | Adrián Hernández | 90 | 2002-2011 | |
| 77 | Thomas Bruce | 85 | 1980-1992 | |
| 78 | Lorenzo Deleón | 84 | 1989-2000 | |
| 79 | Cristo Beltrán | 83 | 1973-1985 | |
| 79 | Jamal Dawe | 83 | 1959-1966 | |
| 79 | Joey Williams | 83 | 1994-2008 | |
| 82 | Doug Moss# | 82 | 2005-2014 | |
| 82 | Daniel Tilly | 82 | 1959-1970 | |
| 84 | Alberto Torres | 81 | 1965-1972 | |
| 85 | Garrett Rivers | 80 | 1975-1990 | |
| 86 | Carl García# | 79 | 2007-2014 | |
| 87 | Wesley Andrews | 77 | 1994-2005 | |
| 87 | Brian Dunn | 77 | 1982-1993 | |
| 87 | Mark McClain | 77 | 1969-1978 | |
| 87 | Harvey Priddy | 77 | 1967-1979 | |
| 91 | R.J. Fleming | 76 | 1970-1982 | |
| 92 | Ignacio Chávez | 75 | 1991-1995 | |
| 93 | Julián Enríquez# | 73 | 2006-2014 | |
| 94 | Dennis Sparks | 72 | 1995-2002 | |
| 95 | Robert Wright# | 71 | 2005-2014 | |
| 96 | Preston Lee# | 70 | 2004-2014 | |
| 97 | Francisco Galván | 69 | 1998-2010 | |
| 98 | Chris Boswell | 68 | 1980-1991 | |
| 98 | Jesús Martínez | 68 | 1996-2002 | |
| 98 | Mal McGinnis | 68 | 1980-1992 |
