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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Pedro González | 377 | 1989-2006 | |
| 2 | Felipe García | 339 | 1963-1978 | |
| 3 | Raymond Stephens* | 316 | 1953-1973 | |
| 4 | Ogai Toyota* | 273 | 1964-1980 | |
| 5 | Douglas Thornton | 257 | 1952-1971 | |
| 6 | Jesús Antonio | 228 | 1988-1996 | |
| 7 | Joseph Izquierdo* | 227 | 1956-1976 | |
| 8 | Mario Padilla# | 225 | 2001-2014 | |
| 9 | Heriberto Gonzalez* | 222 | 1957-1965 | |
| 10 | António Evans | 218 | 1994-2011 | |
| 11 | Wayne Maynard | 208 | 1977-1988 | |
| 12 | Gustavo Javier | 194 | 1989-2001 | |
| 13 | Phil Farmer | 186 | 1992-2003 | |
| 14 | Héctor Carrillo | 179 | 1972-1984 | |
| 15 | Jorge Sandoval | 170 | 1972-1986 | |
| 16 | José Muñíz# | 164 | 1998-2013 | |
| 17 | Luis Martínez | 159 | 1977-1995 | |
| 18 | Lance Islam | 149 | 1958-1976 | |
| 19 | Eugene Vogl | 148 | 1952-1966 | |
| 20 | Ricardo Rivas# | 145 | 2004-2014 | |
| 21 | Andrew Woolum | 143 | 1956-1972 | |
| 22 | Julián Villarreal | 142 | 1987-1995 | |
| 23 | Michael Cude | 141 | 1952-1967 | |
| 24 | César Morales | 139 | 1980-1997 | |
| 25 | Troy Frazier# | 136 | 1998-2014 | |
| 26 | Emílio Martínez | 134 | 1996-2008 | |
| 27 | Cory Black# | 133 | 1998-2014 | |
| 27 | Kenny Harper | 133 | 1964-1976 | |
| 29 | Eddy Watts | 129 | 1987-2002 | |
| 30 | José Garza | 128 | 1986-2000 | |
| 31 | Todd Hill | 127 | 1985-1997 | |
| 32 | Jorge Guzmán | 123 | 1984-2000 | |
| 32 | César Ortíz | 123 | 1963-1977 | |
| 34 | Kwang-rak Sip | 119 | 1988-1999 | |
| 35 | Juan Deleón | 111 | 1998-2013 | |
| 36 | Dave Shaffer# | 110 | 2003-2014 | |
| 37 | Bob Campbell | 107 | 1978-1992 | |
| 38 | Wouter Janse | 103 | 1968-1981 | |
| 39 | Drake Newman | 102 | 1996-2001 | |
| 40 | John O'Neal | 101 | 1962-1973 | |
| 41 | Ralph Simpson | 100 | 1976-1991 | |
| 42 | Jeff Hyde# | 99 | 2001-2014 | |
| 43 | Gary Anslow | 98 | 1998-2011 | |
| 43 | Henry Eatwell* | 98 | 1982-2004 | |
| 45 | Paul Davis* | 97 | 1952-1964 | |
| 46 | Floyd Hayes | 96 | 1985-1997 | |
| 46 | Alonso Maldonado# | 96 | 2010-2014 | |
| 46 | Keith Price* | 96 | 1960-1984 | |
| 49 | Álex Muñóz | 95 | 1964-1980 | |
| 50 | Carlton Fletcher | 94 | 1968-1977 | |
| 51 | Garry MacAusland | 91 | 1997-2007 | |
| 52 | Steve Martin | 90 | 2000-2011 | |
| 53 | Nathan Bartlett# | 89 | 2010-2014 | |
| 54 | Tony Dejens | 88 | 1988-2000 | |
| 54 | John Mota | 88 | 1952-1964 | |
| 56 | Skip Moon | 87 | 1984-1998 | |
| 57 | Andrew McCoy | 85 | 1971-1980 | |
| 58 | David Hindman | 79 | 1955-1967 | |
| 59 | Trevor Seals* | 76 | 1969-1991 | |
| 59 | Robert Villarreal | 76 | 1998-2007 | |
| 61 | Alejandro Sánchez | 74 | 1965-1978 | |
| 62 | Héctor Freitas | 73 | 1991-2003 | |
| 62 | Bill Jones | 73 | 1982-2001 | |
| 62 | Joe Whelan* | 73 | 1952-1964 | |
| 65 | Dudley Langworthy | 72 | 1952-1965 | |
| 66 | José González# | 71 | 2002-2013 | |
| 67 | Sherman Farley | 68 | 1963-1973 | |
| 68 | Thad Carrillo | 67 | 1958-1970 | |
| 68 | Michael Cook | 67 | 1965-1972 | |
| 68 | Frank Moore | 67 | 1963-1975 | |
| 71 | Bob Jenkins | 66 | 1985-1995 | |
| 72 | Roberto Castro# | 65 | 2008-2014 | |
| 72 | Sam Morrison | 65 | 1963-1971 | |
| 74 | Pedro Castro# | 62 | 2003-2014 | |
| 74 | Jeff Hurst | 62 | 1966-1978 | |
| 74 | Ian Xiao | 62 | 2003-2010 | |
| 77 | Jesus Abreu | 61 | 1959-1967 | |
| 77 | Jeffery MacCaul | 61 | 1974-1983 | |
| 79 | Pete Goodman# | 60 | 2003-2011 | |
| 79 | Miguel Martínez | 60 | 1977-1987 | |
| 79 | Freddie Smith | 60 | 1970-1983 | |
| 82 | Larry Adams | 59 | 1963-1972 | |
| 82 | Jimmy Bickle | 59 | 1986-2001 | |
| 84 | Walter Salgado | 58 | 1952-1965 | |
| 84 | Jared Walsh | 58 | 1974-1985 | |
| 86 | Héctor Romero | 57 | 1966-1974 | |
| 87 | Guastão Dorneles | 56 | 1985-1996 | |
| 88 | Ron Davis# | 55 | 2006-2013 | |
| 88 | Ray Garrett | 55 | 1960-1970 | |
| 88 | Christian Green | 55 | 1978-1988 | |
| 91 | Lamont Diez | 53 | 1957-1972 | |
| 91 | Luis Mogro | 53 | 1963-1974 | |
| 91 | Paul Puleston | 53 | 1969-1980 | |
| 94 | Stanley Manley | 52 | 1985-1991 | |
| 95 | Cris Espinosa | 50 | 1981-1995 | |
| 96 | Jesús Flores | 49 | 1984-2001 | |
| 96 | Jonathan Irick | 49 | 1955-1961 | |
| 96 | Tyler Lee# | 49 | 2003-2014 | |
| 99 | William Ballard | 48 | 1974-1983 | |
| 99 | Bryant Lewis | 48 | 1968-1983 |
