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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Nelson Padilla | 242 | 1999-2014 | |
| 2 | Christian Piper | 241 | 1998-2007 | |
| 3 | António Násquez | 238 | 1994-2006 | |
| 4 | Scott Antonio | 211 | 1996-2010 | |
| 4 | Pablo Lugo | 211 | 1991-2005 | |
| 6 | Bill Price# | 204 | 2003-2014 | |
| 7 | Lee Dailey | 203 | 1957-1967 | |
| 8 | Ed Curran# | 202 | 2002-2014 | |
| 8 | John Johnson | 202 | 1969-1976 | |
| 10 | Murray Gallagher | 200 | 1993-2004 | |
| 11 | Thomas Clayton | 198 | 1975-1983 | |
| 12 | Ron Oliver | 190 | 1964-1975 | |
| 13 | Mario Álvarez | 188 | 1977-1986 | |
| 14 | Dave Beadle | 187 | 1960-1969 | |
| 14 | Brad Brooks | 187 | 1999-2009 | |
| 16 | Randy Laidlaw | 186 | 1988-2000 | |
| 17 | Randy De Jesús | 185 | 1993-2005 | |
| 17 | Tony Lowe | 185 | 1968-1981 | |
| 19 | Terry Laing | 181 | 1957-1966 | |
| 20 | Eric Kemp | 176 | 1969-1978 | |
| 21 | Mike Roberts | 173 | 1998-2011 | |
| 21 | Raymond Wright | 173 | 1975-1981 | |
| 23 | John Crow | 167 | 1983-1992 | |
| 24 | António González | 166 | 1971-1984 | |
| 24 | Jesús Romero | 166 | 1981-1989 | |
| 26 | Terry Abrego | 165 | 1983-1992 | |
| 26 | Frank LeBlanc | 165 | 1967-1983 | |
| 26 | Sean Ward | 165 | 1967-1975 | |
| 26 | Rodrigo Ávila | 165 | 2000-2008 | |
| 30 | Jeff Cook | 162 | 1989-2005 | |
| 30 | Toby Nix | 162 | 1983-1992 | |
| 32 | Paco Flores | 161 | 1992-2003 | |
| 32 | Ray Neal | 161 | 1991-1999 | |
| 34 | Edgar Geil | 160 | 1957-1969 | |
| 34 | Pablo Águila | 160 | 1992-2004 | |
| 36 | Larry Hines | 158 | 1982-1995 | |
| 37 | Theodore Snow | 153 | 1988-1995 | |
| 38 | William Piscitelli | 152 | 1957-1970 | |
| 39 | Jesús De La Rosa | 150 | 1987-1995 | |
| 40 | Roy Mann | 149 | 1964-1977 | |
| 41 | Ben Moore | 148 | 1974-1981 | |
| 41 | Jason Moore | 148 | 1962-1973 | |
| 41 | Júlio Rocha# | 148 | 2001-2014 | |
| 44 | Andy Carroll | 147 | 1980-1991 | |
| 44 | Roger Francis# | 147 | 2004-2014 | |
| 46 | Ray Hawkins | 146 | 1991-2001 | |
| 47 | Carlos Camacho# | 144 | 2000-2014 | |
| 48 | Yorikane Ishii | 142 | 2002-2010 | |
| 48 | Felipe Medina | 142 | 2001-2011 | |
| 48 | Omar Romero | 142 | 1995-2001 | |
| 51 | Shannon Bowie | 141 | 1957-1968 | |
| 52 | Esteban Aguirre | 139 | 1995-2008 | |
| 52 | Wallace Simmons | 139 | 1984-1991 | |
| 52 | Robbie Stuart | 139 | 1987-1995 | |
| 55 | Alberto Ruíz | 138 | 1969-1975 | |
| 56 | Alexis Carroll | 137 | 1986-1993 | |
| 56 | Bill Mitchell | 137 | 1966-1977 | |
| 56 | Arturo Vázquez# | 137 | 2002-2014 | |
| 59 | Sergio Maldonado | 136 | 1962-1975 | |
| 60 | Jerry Fernández | 135 | 2000-2010 | |
| 60 | Al Fletcher | 135 | 1984-1993 | |
| 60 | Santiago Gómez | 135 | 1966-1979 | |
| 63 | Júlio Velázquez | 134 | 1986-1993 | |
| 64 | Richard Blevins | 133 | 1965-1975 | |
| 64 | Andrew Sullivan | 133 | 1987-1999 | |
| 66 | Chester Bailey | 132 | 1972-1986 | |
| 66 | Lee Howard# | 132 | 2003-2012 | |
| 68 | Richard Heim | 131 | 1980-1992 | |
| 68 | Brian Morgan | 131 | 1978-1985 | |
| 70 | António Gallardo | 130 | 1996-2009 | |
| 71 | Jaime Rosado | 129 | 1993-2004 | |
| 72 | Phil Longchamps# | 128 | 2005-2014 | |
| 72 | Tim Miller | 128 | 1970-1977 | |
| 74 | John Bang | 126 | 1959-1968 | |
| 74 | Denny Black | 126 | 1973-1984 | |
| 74 | Jeremiah Burrowes | 126 | 1990-1998 | |
| 74 | Richard Mayor | 126 | 1957-1969 | |
| 74 | Gil O'Rourke | 126 | 1983-1989 | |
| 74 | Roger Patterson | 126 | 1993-1999 | |
| 74 | Roberto Vázquez | 126 | 1989-2002 | |
| 81 | Matt Alemán# | 125 | 2002-2014 | |
| 81 | Bob Coleman# | 125 | 2004-2014 | |
| 81 | Burgess Zimmerman | 125 | 1971-1977 | |
| 84 | César Hernández | 124 | 1982-1992 | |
| 84 | José Rodríguez | 124 | 1993-2008 | |
| 86 | Robbie Moore | 123 | 1970-1983 | |
| 87 | Jon Frierson | 122 | 1959-1970 | |
| 87 | Jeffrey Patterson | 122 | 1991-1997 | |
| 87 | Robert Wilson | 122 | 1979-1985 | |
| 87 | Richie Wise | 122 | 1980-1987 | |
| 91 | Carlos De Jesús | 121 | 1968-1979 | |
| 91 | Sherwood Gilbert | 121 | 1997-2006 | |
| 91 | Jim Gould | 121 | 1998-2006 | |
| 94 | Claudio González | 120 | 1994-2002 | |
| 94 | Felipe Valdéz | 120 | 1999-2007 | |
| 94 | Gary Whittier | 120 | 1967-1975 | |
| 97 | Alexis Buchanan | 119 | 1994-2004 | |
| 97 | Martin Martínez | 119 | 1993-2000 | |
| 97 | Bennett Owens | 119 | 1975-1985 | |
| 100 | Ralph Frank | 118 | 1987-1995 |
