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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Loren Herman | 1.958 | 1966-1982 | |
| 2 | Russ Scott | 2.200 | 1976-1992 | |
| 3 | Manuel Cline | 2.233 | 1991-2005 | |
| 4 | Francisco Lucero | 2.284 | 1968-1983 | |
| 5 | José Luna | 2.308 | 1970-1983 | |
| 6 | Leonard Bader* | 2.318 | 1978-1999 | |
| 7 | Tom Holz | 2.339 | 1980-1993 | |
| 8 | Dan Cooke | 2.388 | 1976-1991 | |
| 9 | Curtis Graves* | 2.540 | 1978-1991 | |
| 10 | Felipe Garza* | 2.541 | 1979-1998 | |
| 11 | Won-sub Pak* | 2.550 | 1968-1983 | |
| 12 | Luther Hawks | 2.584 | 1981-1995 | |
| 13 | Adrián Hernández | 2.590 | 1976-1991 | |
| 14 | Chris Thomas | 2.598 | 1970-1989 | |
| 15 | Michael Callahan | 2.613 | 1975-1994 | |
| 16 | Carlos Westacott | 2.635 | 1981-1996 | |
| 17 | Bryan Hill | 2.670 | 1982-1996 | |
| 18 | Santiago Olivas | 2.694 | 1965-1984 | |
| 18 | Larry Adams# | 2.694 | 2003-2014 | |
| 20 | Jorge Romero | 2.701 | 1963-1981 | |
| 21 | Gonzalo Mesa | 2.718 | 1992-2004 | |
| 22 | John Wilson* | 2.738 | 1972-1989 | |
| 23 | Domingo Morán* | 2.742 | 1975-1989 | |
| 24 | Bill Henderson* | 2.749 | 1978-1993 | |
| 25 | Dan Soto* | 2.755 | 1984-2000 | |
| 26 | John Clark | 2.758 | 1969-1985 | |
| 27 | César Hidalgo | 2.772 | 1972-1983 | |
| 28 | Edward Whatley | 2.780 | 1997-2011 | |
| 29 | Loren Blair | 2.790 | 2002-2014 | |
| 30 | Bill Greene* | 2.805 | 1988-2004 | |
| 31 | Cody Watson | 2.822 | 1981-1994 | |
| 32 | Jesús López | 2.836 | 1992-2003 | |
| 33 | Andrew Bowling | 2.849 | 1973-1985 | |
| 34 | Julián Vélez | 2.851 | 1992-2006 | |
| 35 | Don Parkinson | 2.854 | 1991-2000 | |
| 36 | Nathan Fleming | 2.899 | 1981-1993 | |
| 37 | Christopher Davis | 2.904 | 1974-1988 | |
| 38 | Sergio Estrada# | 2.908 | 2007-2014 | |
| 39 | Will Daniel | 2.923 | 1981-1993 | |
| 39 | Gabriel Ordóñez# | 2.923 | 2002-2014 | |
| 41 | Tyson Martin | 2.926 | 1989-2000 | |
| 42 | José Crespo | 2.928 | 1980-1991 | |
| 43 | Ramón Cruz* | 2.934 | 1980-2001 | |
| 43 | Paul Sizemore | 2.934 | 1981-2000 | |
| 45 | Cristo Alvarado# | 2.935 | 1999-2014 | |
| 46 | Jaime Román | 2.938 | 1989-2007 | |
| 47 | Luis Reyes# | 2.957 | 2002-2014 | |
| 48 | Shunen Hasegawa | 2.970 | 1988-1996 | |
| 49 | Pablo Contreras* | 2.973 | 1970-1985 | |
| 50 | John Cordero | 2.974 | 1989-2003 | |
| 51 | Scott Wilson* | 2.981 | 1971-1987 | |
| 52 | Alex Dávila# | 2.984 | 1997-2014 | |
| 53 | Sam Law | 3.018 | 1983-2000 | |
| 54 | Francisco Villegas | 3.027 | 1997-2012 | |
| 54 | Carlos Morales | 3.027 | 1976-1991 | |
| 56 | John Hernández | 3.030 | 1998-2014 | |
| 57 | José Sánchez | 3.031 | 1987-1998 | |
| 58 | Curt Crowder | 3.032 | 1972-1987 | |
| 59 | David Eichelberger# | 3.034 | 2004-2014 | |
| 60 | Pedro Hardy# | 3.041 | 2006-2014 | |
| 61 | Cameron Miller | 3.047 | 1993-2003 | |
| 62 | Bob Dickey* | 3.051 | 1972-1993 | |
| 63 | Tyrone Sharp | 3.053 | 1991-2004 | |
| 64 | José Ortíz | 3.057 | 1995-2009 | |
| 65 | Donald Martin | 3.064 | 1975-1989 | |
| 66 | Don Gardner | 3.084 | 1980-1996 | |
| 67 | Bill Rankin | 3.092 | 2000-2012 | |
| 67 | Larry Robinson | 3.092 | 1984-1999 | |
| 69 | Diego Cruz | 3.098 | 1997-2012 | |
| 70 | Curt Murphy | 3.104 | 1967-1986 | |
| 70 | Jackson Mendoza# | 3.104 | 2008-2014 | |
| 72 | James Thomas# | 3.105 | 2002-2014 | |
| 73 | Mike Ackerman | 3.106 | 1969-1984 | |
| 74 | John Hawkins | 3.107 | 1998-2007 | |
| 75 | Kevin Benton | 3.109 | 1987-2005 | |
| 76 | José Díaz | 3.113 | 1982-1992 | |
| 77 | Thomas Kennedy | 3.119 | 1965-1974 | |
| 78 | Claude Booker | 3.128 | 1994-2007 | |
| 79 | Dave Sackett# | 3.134 | 2008-2014 | |
| 80 | José García | 3.138 | 1993-2006 | |
| 80 | Mike Walker | 3.138 | 1980-1997 | |
| 82 | Andy Gilmore | 3.142 | 1993-2009 | |
| 83 | Lou Reyes | 3.152 | 1994-2006 | |
| 84 | Odwin van de Par | 3.154 | 1997-2007 | |
| 85 | Orlando García# | 3.159 | 2004-2014 | |
| 86 | Paco Román | 3.168 | 1961-1976 | |
| 87 | Daniel Jenkins | 3.178 | 1954-1970 | |
| 88 | Tony Soto# | 3.182 | 2005-2014 | |
| 89 | Jorge Rosa | 3.184 | 1980-1991 | |
| 90 | Werner Kelly | 3.196 | 1983-1998 | |
| 91 | Michael Melton | 3.199 | 1991-2007 | |
| 92 | Mark Robinson | 3.200 | 1984-1998 | |
| 93 | Pedro Romero# | 3.203 | 2002-2014 | |
| 94 | Bob Moss | 3.213 | 1962-1978 | |
| 95 | Cecil Lozano | 3.217 | 1992-2005 | |
| 95 | Dustin Hines | 3.217 | 1995-2011 | |
| 97 | Eric Bell | 3.219 | 1992-2001 | |
| 98 | Javier Estrada# | 3.241 | 2000-2014 | |
| 99 | James Dunlap | 3.244 | 1957-1978 | |
| 100 | Dan-zu Sen# | 3.246 | 2003-2014 |
