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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Alexis Aguiar | 633 | 1953-1970 | |
| 2 | Carlos García | 590 | 1987-2005 | |
| 3 | Reginald Lawrence* | 527 | 1969-1985 | |
| 4 | Brad Taylor* | 513 | 1962-1976 | |
| 5 | Gary Arsenault* | 509 | 1985-2003 | |
| 6 | Morgan Hoskins | 499 | 1968-1984 | |
| 7 | Christopher Isabel | 494 | 1960-1973 | |
| 8 | Winston Sarno | 476 | 1959-1975 | |
| 9 | Donald Smith | 466 | 1954-1970 | |
| 10 | William Butler | 462 | 1978-1994 | |
| 11 | Edward McFarland | 455 | 1992-2005 | |
| 12 | Wayne Mayfield* | 454 | 1982-1999 | |
| 13 | Robert Wyss | 448 | 1959-1972 | |
| 14 | Fabian Cordova | 437 | 1952-1964 | |
| 15 | Joe Banks* | 433 | 1963-1983 | |
| 16 | Juan Rodríguez | 431 | 1968-1983 | |
| 17 | Mike Buck* | 428 | 1983-2004 | |
| 18 | William Brown | 426 | 1955-1969 | |
| 19 | Jaime Román | 421 | 1989-2007 | |
| 20 | Austin Deel | 414 | 1953-1968 | |
| 21 | Clemente Vilas* | 413 | 1953-1969 | |
| 22 | Tony Hilliard | 411 | 1975-1988 | |
| 22 | Benjamin Ridings | 411 | 1955-1969 | |
| 24 | Bruce Marquette | 409 | 1957-1973 | |
| 25 | William Defranco | 408 | 1957-1972 | |
| 26 | John Jenkins | 407 | 1959-1971 | |
| 27 | Kevin Kopecky | 399 | 1958-1969 | |
| 28 | Daniel Avis | 394 | 1958-1973 | |
| 29 | David Cote | 392 | 1990-2005 | |
| 30 | Rupert Spenser | 390 | 1957-1970 | |
| 31 | Roger Gardea | 387 | 1954-1969 | |
| 32 | Ricardo Ruíz | 386 | 1987-2001 | |
| 33 | Pablo Herrero | 383 | 1956-1970 | |
| 33 | Millard Peterson | 383 | 1967-1979 | |
| 35 | Enrique Franco | 381 | 1983-1998 | |
| 36 | Ruben Ibarra | 379 | 1952-1963 | |
| 37 | Elijah Yates* | 377 | 1984-2001 | |
| 38 | Derrick Tiedeman | 376 | 1959-1975 | |
| 39 | Ramón Cruz* | 375 | 1980-2001 | |
| 40 | Marty Myers | 374 | 1962-1977 | |
| 41 | Rubén Lerma | 368 | 1964-1978 | |
| 42 | Harry Pettitt | 365 | 1952-1969 | |
| 43 | Ricardo López | 360 | 1995-2009 | |
| 44 | Dave Pryor | 358 | 1981-1993 | |
| 45 | Kenneth Sartin | 357 | 1959-1971 | |
| 46 | Julián Camacho | 356 | 1995-2010 | |
| 46 | George Ogren | 356 | 1952-1969 | |
| 48 | Dean McGinnity | 355 | 1962-1974 | |
| 49 | Michael David | 354 | 1966-1978 | |
| 50 | Jorge Estrada | 352 | 1978-1994 | |
| 51 | Carl Nicosia* | 349 | 1952-1963 | |
| 51 | George Wedel | 349 | 1953-1968 | |
| 53 | Walter Mann | 343 | 1959-1971 | |
| 53 | Clyde Pearson | 343 | 1952-1965 | |
| 55 | Vernon Frazier* | 342 | 1976-1997 | |
| 55 | Rafael Randín | 342 | 1986-2000 | |
| 55 | Sergio Vela* | 342 | 1972-1996 | |
| 58 | Lee Smith | 339 | 1959-1969 | |
| 58 | Gregory West | 339 | 1957-1971 | |
| 60 | Dan Gilbert | 338 | 1966-1982 | |
| 60 | Robert Hyler | 338 | 1958-1969 | |
| 60 | Javier Urrutia | 338 | 1958-1973 | |
| 63 | Won-sub Pak* | 337 | 1968-1983 | |
| 64 | Joe Bean | 333 | 1974-1987 | |
| 64 | Randy Chupp | 333 | 1952-1968 | |
| 64 | Nate Lindsey | 333 | 2000-2013 | |
| 64 | Chester McCarley | 333 | 1957-1973 | |
| 64 | Carlos Pacheco | 333 | 1974-1988 | |
| 69 | Glenn Calhoun | 328 | 1962-1979 | |
| 69 | Rod Duncan | 328 | 1986-1998 | |
| 71 | Chris Myers | 327 | 1992-2006 | |
| 72 | Dave Hunter | 325 | 1968-1982 | |
| 73 | Ariel Villegas | 324 | 1958-1976 | |
| 74 | Robert Hile | 323 | 1958-1969 | |
| 75 | Benedict Gates | 322 | 1978-1992 | |
| 75 | Mark Parker | 322 | 1965-1976 | |
| 77 | Alexander Lenihan | 319 | 1952-1965 | |
| 78 | Tim Bane | 318 | 1990-2006 | |
| 79 | Pedro Navarro | 316 | 1995-2012 | |
| 80 | Charles Weimer | 315 | 1961-1974 | |
| 81 | Tyler Walker | 314 | 1995-2009 | |
| 82 | Gerald Adkisson | 313 | 1952-1964 | |
| 82 | Cristo Alvarado# | 313 | 1999-2014 | |
| 82 | Félix Brito# | 313 | 1999-2014 | |
| 82 | José Cuellar | 313 | 1969-1985 | |
| 82 | Alejandro Quintero | 313 | 1996-2012 | |
| 87 | Juan Carlos Cervantes | 312 | 1967-1978 | |
| 87 | Bob MacAlduie | 312 | 1985-2002 | |
| 87 | Alberto Reyna | 312 | 1963-1976 | |
| 87 | Julian Wood* | 312 | 1962-1977 | |
| 91 | Alex Dávila# | 311 | 1997-2014 | |
| 92 | Jeff Horswill | 309 | 1992-2008 | |
| 92 | Valter Ribadeneira | 309 | 1963-1975 | |
| 94 | Miguel Meléndez | 308 | 1995-2013 | |
| 94 | Dante Ruiz* | 308 | 1952-1962 | |
| 96 | John Bishop | 305 | 1979-1992 | |
| 96 | George Cole | 305 | 1982-1998 | |
| 96 | Francisco Villegas | 305 | 1997-2012 | |
| 99 | Félix Medina | 304 | 1969-1984 | |
| 100 | Raúl Hernández# | 303 | 1999-2014 |
