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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Adolfo Napoleoni# | 36 | 1995-2015 | |
| 2 | Raymond Stephens* | 30 | 1953-1973 | |
| 3 | Kent Gordon* | 28 | 1967-1982 | |
| 3 | Dusty O'Lehan | 28 | 1967-1983 | |
| 5 | Tommy Chávez | 27 | 1986-1998 | |
| 6 | Felipe García | 26 | 1963-1978 | |
| 7 | Dean Campanelli | 25 | 1960-1971 | |
| 7 | Kurt Todd* | 25 | 1977-1998 | |
| 9 | Millard Brandon* | 24 | 1979-1993 | |
| 9 | Robert Edmonds | 24 | 1958-1975 | |
| 9 | Dan Kerry* | 24 | 1981-1997 | |
| 12 | Chris Anderson* | 23 | 1974-1986 | |
| 12 | Tyler Daniels* | 23 | 1977-1994 | |
| 12 | Wilson Gonzáles* | 23 | 1978-2000 | |
| 12 | Kenny Harper | 23 | 1964-1976 | |
| 12 | John Krum | 23 | 1956-1974 | |
| 17 | Ken Moran* | 21 | 1969-1982 | |
| 17 | David Reed* | 21 | 1957-1973 | |
| 17 | Otto Reed# | 21 | 2001-2015 | |
| 20 | Marcos Garza# | 20 | 2005-2015 | |
| 21 | Dan Gorst* | 19 | 1977-1993 | |
| 21 | Steven Riddick* | 19 | 1958-1979 | |
| 21 | Tom Schaefer* | 19 | 1972-1989 | |
| 21 | Arturo Vega | 19 | 1982-1998 | |
| 25 | Cory Ashburn* | 18 | 1955-1970 | |
| 25 | Denver Dean* | 18 | 1984-1997 | |
| 25 | Ronald Fegan | 18 | 1953-1969 | |
| 25 | Derek Fisher | 18 | 1967-1977 | |
| 25 | Kent Gordon | 18 | 1996-2012 | |
| 25 | Joseph Izquierdo* | 18 | 1956-1976 | |
| 25 | Tomás Reyes | 18 | 1969-1982 | |
| 25 | Evan Underwood | 18 | 1991-2002 | |
| 25 | José Vásquez# | 18 | 2001-2015 | |
| 25 | Sung-heun Yi | 18 | 1969-1986 | |
| 35 | Jesús Escobar | 17 | 1992-2007 | |
| 35 | Jorge Galindo | 17 | 1962-1977 | |
| 35 | Caleb Riley | 17 | 1997-2014 | |
| 38 | José Alarcon# | 16 | 2004-2015 | |
| 38 | Travis Fitzgerald | 16 | 1971-1984 | |
| 38 | Pedro García | 16 | 1999-2014 | |
| 38 | Lonnie Knowles | 16 | 1968-1980 | |
| 38 | Keith Price* | 16 | 1960-1984 | |
| 38 | Hayden Reese# | 16 | 2001-2015 | |
| 38 | Trevor Seals* | 16 | 1969-1991 | |
| 38 | Juan Yan* | 16 | 1960-1974 | |
| 46 | Carl Barden | 15 | 1980-1992 | |
| 46 | Paul Best | 15 | 1984-1996 | |
| 46 | Jorge García# | 15 | 2003-2015 | |
| 46 | António González* | 15 | 1979-1994 | |
| 46 | Diego Hernández# | 15 | 2008-2015 | |
| 46 | Bill Jones | 15 | 1982-2001 | |
| 46 | Gilberto Lugo# | 15 | 2008-2015 | |
| 46 | Ray O'Day* | 15 | 1973-1989 | |
| 46 | Roberto Pacheco | 15 | 1999-2013 | |
| 46 | Dave Shaffer# | 15 | 2003-2015 | |
| 46 | Mike Williamson | 15 | 1981-1999 | |
| 57 | Lionel Chavez | 14 | 1959-1966 | |
| 57 | Carlos Mora# | 14 | 2002-2015 | |
| 57 | Tsukasa Nakamura | 14 | 1996-2010 | |
| 57 | José Quiñones | 14 | 1995-2006 | |
| 57 | Bob Simon | 14 | 1979-1992 | |
| 57 | Carl Smith | 14 | 1963-1979 | |
| 57 | Peter Sánchez | 14 | 1996-2013 | |
| 57 | Eduardo Vega# | 14 | 2002-2015 | |
| 65 | Cory Black# | 13 | 1998-2015 | |
| 65 | Seth Henry | 13 | 1980-1996 | |
| 65 | Mario Padilla# | 13 | 2001-2015 | |
| 65 | Germán Palmeiro | 13 | 1978-1991 | |
| 65 | José Ramírez | 13 | 1979-1989 | |
| 65 | Pedro Rivera | 13 | 1982-1995 | |
| 65 | William Rowe* | 13 | 1959-1977 | |
| 65 | Glenn Thompson | 13 | 1979-1992 | |
| 65 | David Wallace | 13 | 1996-2008 | |
| 74 | Christopher Davis | 12 | 1960-1974 | |
| 74 | Daniel Fernández# | 12 | 2011-2015 | |
| 74 | Félix Ferrer | 12 | 1986-1999 | |
| 74 | Albert Gallegos | 12 | 1998-2013 | |
| 74 | Pedro González | 12 | 1989-2006 | |
| 74 | Floyd Hayes | 12 | 1985-1997 | |
| 74 | Jessie Hughes | 12 | 1979-1991 | |
| 74 | Andrew Lucas | 12 | 1970-1983 | |
| 74 | Carlos Molina | 12 | 1969-1979 | |
| 74 | Don Smith | 12 | 1971-1986 | |
| 74 | Ogai Toyota* | 12 | 1964-1980 | |
| 74 | Mason Webb | 12 | 1955-1966 | |
| 74 | Brigham White* | 12 | 1964-1980 | |
| 74 | Dennis Williams | 12 | 1991-2007 | |
| 88 | John Adams | 11 | 1990-2004 | |
| 88 | Campbell Broomhead# | 11 | 2006-2015 | |
| 88 | Billy Bunch# | 11 | 2010-2015 | |
| 88 | José Camacho | 11 | 1968-1978 | |
| 88 | António Evans | 11 | 1994-2011 | |
| 88 | Phil Farmer | 11 | 1992-2003 | |
| 88 | Víctor Fernández* | 11 | 1962-1985 | |
| 88 | Heriberto Gonzalez* | 11 | 1957-1965 | |
| 88 | Dwayne Johnson* | 11 | 1987-2004 | |
| 88 | Rob Knight# | 11 | 2004-2015 | |
| 88 | Peter Martin | 11 | 1976-1988 | |
| 88 | Steven McClay | 11 | 1960-1976 | |
| 88 | Johnny Mullins | 11 | 1973-1982 |
